Hubungan Kepatuhan Minum Obat Terhadap Tingkat Perbaikan Gejala Skizofrenia Di Rumah Sakit TNI Angkatan Laut Dr. Mintohardjo

Muhammad Fasah Bahrul Alam, . (2025) Hubungan Kepatuhan Minum Obat Terhadap Tingkat Perbaikan Gejala Skizofrenia Di Rumah Sakit TNI Angkatan Laut Dr. Mintohardjo. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Schizophrenia is a chronic mental disorder with a high relapse rate, strongly influenced by patients’ adherence to treatment. Non-adherence is often the main cause of symptom deterioration, and although pharmacological therapy cannot fully cure schizophrenia, regular medication intake has been proven to reduce symptom severity. This study aimed to examine the association between medication adherence and symptom improvement in outpatients with schizophrenia at Dr. Mintohardjo Naval Hospital during May 2025. Using an observational analytic cross-sectional design and total sampling technique, 11 patients who met the inclusion criteria were enrolled. Data were collected from initial and final PANSS scores and medication adherence was assessed using the MMAS-8 questionnaire. Statistical analysis included Shapiro-Wilk, homogeneity testing, One-Way ANOVA, and Post Hoc Tukey HSD. The results showed that most patients (54.5%) demonstrated high adherence with significant reductions in PANSS scores, where ANOVA revealed p=0.010 and an average reduction of 24.00. Further analysis with Tukey HSD confirmed a significant difference between high- and low-adherence groups (p=0.008). In conclusion, medication adherence was significantly associated with symptom improvement, with highly adherent patients experiencing greater improvements compared to those with moderate or low adherence.

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 2110211113] [Pembimbing 1: Ria Maria Theresa] [Pembimbing 2: Yosha Putri Wahyuni] [Penguji: Melly Kristanti]
Uncontrolled Keywords: Schizophrenia, Medication Adherence, PANSS, Symptom Improvement
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: MUHAMMAD FASAH BAHRUL ALAM
Date Deposited: 08 Sep 2025 03:45
Last Modified: 08 Sep 2025 03:45
URI: http://repository.upnvj.ac.id/id/eprint/39930

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