Annisa Hasna Nabila, . (2026) ANALISIS EFEKTIVITAS BIAYA KOMBINASI METFORMIN-GLIQUIDONE DAN METFORMIN-GLIMEPIRIDE PADA PASIEN RAWAT JALAN DIABETES MELITUS TIPE 2 DI RSUP PERSAHABATAN PERIODE 2024. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
Type 2 diabetes mellitus is a condition associated with substantial treatment expenditures and a significant burden on the National Health Insurance (JKN), often causing losses to hospitals, thus requiring effective and efficient therapy. This study analyze the cost-effectiveness of combination therapy using metformin-gliquidone versus metformin-glimepiride in outpatients care. This study employed a retrospective observational design using data obtained from patient medical records at Persahabatan General Hospital. Effectiveness was assessed through changes in fasting blood glucose levels, and costs were analyzed from the hospital's perspective, including direct medical costs consisting of administrative costs, physician services, laboratory tests, and medications. The results showed that the metformin-glimepiride combination tended to provide a better reduction in fasting blood glucose levels at a lower cost compared to metformin-gliquidone. The largest component of direct medical costs came from laboratory test costs, followed by physician fees, medication costs, and administrative costs. The interpretation results show that the metformin-glimepiride is dominant and the metformin gliquidone combination is dominated. The study concludes that the metformin-glimepiride combination demonstrates greater cost-effectiveness than the metformin-gliquidone combination, with respective ACER values of Rp145.592 and Rp177.720.
| Item Type: | Thesis (Skripsi) |
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| Additional Information: | [No.Panggil: 2210212016] [Pembimbing: Riswandy Wasir] [Penguji 1: Primayanti Nurul Ilmi] [Penguji 2: Via Rifkia] |
| Uncontrolled Keywords: | Cost-effectiveness, metformin-glimepiride, metformin-gliquidone, type 2 diabetes mellitus |
| Subjects: | R Medicine > RS Pharmacy and materia medica R Medicine > RZ Other systems of medicine |
| Divisions: | Fakultas Kedokteran > Program Studi Farmasi (S1) |
| Depositing User: | ANNISA HASNA NABILA |
| Date Deposited: | 27 Aug 2026 10:42 |
| Last Modified: | 27 Aug 2026 10:42 |
| URI: | http://repository.upnvj.ac.id/id/eprint/50538 |
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