Nabila Khoirunnisa, . (2024) FORMULASI DAN UJI IRITASI SEDIAAN SOOTHING GEL DENGAN VARIASI KONSENTRASI EKSTRAK ETANOL DAUN SIRSAK (ANNONA MURICATA L.). Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
![[img]](http://repository.upnvj.ac.id/style/images/fileicons/text.png) |
Text
ABSTRAK.pdf Download (197kB) |
|
Text
AWAL.pdf Download (735kB) |
|
Text
BAB 1.pdf Restricted to Repository UPNVJ Only Download (204kB) |
|
Text
BAB 2.pdf Restricted to Repository UPNVJ Only Download (614kB) |
|
Text
BAB 3.pdf Restricted to Repository UPNVJ Only Download (461kB) |
|
Text
BAB 4.pdf Restricted to Repository UPNVJ Only Download (480kB) |
|
Text
BAB 5.pdf Download (178kB) |
|
Text
DAFTAR PUSTAKA.pdf Download (263kB) |
|
Text
RIWAYAT HIDUP.pdf Restricted to Repository UPNVJ Only Download (184kB) |
|
Text
LAMPIRAN.pdf Restricted to Repository UPNVJ Only Download (3MB) |
|
Text
HASIL PLAGIARISME.pdf Restricted to Repository staff only Download (13MB) |
|
Text
ARTIKEL KI.pdf Restricted to Repository staff only Download (350kB) |
Abstract
Soothing gel is a moisturizing cosmetic with good absorption, has cool properties when applied, and can reduce redness on the skin. However, natural-based soothing gel products are rarely found in the market. This research is intended to make an innovative soothing gel preparation based on soursop leaf extract. Ultrasonic Assisted Extraction (UAE) method was used to extract soursop leaves. Soothing gel was formulated using soursop leaf extract as the active substance whose value was 2%, 4%, and 6%. After formulation, physical improvement tests were carried out on each formulation including homogeneity, organoleptic, pH, adhesion, spreadability, and viscosity tests. The preparation irritation test was run with vivo using rabbits with the Draize Test technique. The results of the irritation test were that all formulations did not irritate the skin. In summary, the variation in the concentration of soursop leaf ethanol extract as the active ingredient affects the physical evaluation test of soothing gel preparations and the best evaluation results are obtained in soothing gel preparations with 2% soursop leaf extract which are then carried out antioxidant tests for extracts and preparations with IC50 results which are classified as very strong, namely 2.14 and 4.75 ppm.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil:2010212032] [Pembimbing 1: Rika Revina] [Pembimbing 2: Via Rifkia] [Penguji 1: Primayanti Nurul Ilmi] |
| Uncontrolled Keywords: | Soursop leaves, Soothing Gel, Physical Properties Test, Irritation Test, Antioxidant Test |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RL Dermatology R Medicine > RS Pharmacy and materia medica R Medicine > RZ Other systems of medicine |
| Divisions: | Fakultas Kedokteran > Program Studi Farmasi (S1) |
| Depositing User: | NABILA KHOIRUNNISA |
| Date Deposited: | 06 Sep 2024 08:10 |
| Last Modified: | 06 Sep 2024 08:10 |
| URI: | http://repository.upnvj.ac.id/id/eprint/32898 |
Actions (login required)
 |
View Item |