EFEKTIVITAS EKSTRAK RIMPANG LENGKUAS PUTIH (Alpinia galanga) TERHADAP PERTUMBUHAN JAMUR Epidermophyton floccosum PENYEBAB TINEA PEDIS

Fathia Kharitano, . (2023) EFEKTIVITAS EKSTRAK RIMPANG LENGKUAS PUTIH (Alpinia galanga) TERHADAP PERTUMBUHAN JAMUR Epidermophyton floccosum PENYEBAB TINEA PEDIS. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Tinea pedis is a common dermatophyte infection caused by the fungus Epidermophyton floccosum. White galangal (Alpinia galanga), known to contain compounds such as alkaloids, flavonoids, tannins, phenols, and triterpenoids, has the potential for treating fungal infections. This research employed an experimental method using the well diffusion technique. White galangal rhizomes were extracted through maceration for 2 days using 70% ethanol as the solvent. Concentrations of the extract studied were 10%, 20%, 30%, 40%, and 50%. Ketoconazole 2% was used as the positive control, while distilled water served as the negative control, and observations were made for 2 x 24 hours. Data analysis was performed using the Kruskal-Wallis test and Mann-Whitney Post-Hoc test. The research findings indicate that white galangal rhizome (Alpinia galanga) extract significantly inhibits the growth of Epidermophyton floccosum. The most effective concentration in inhibiting fungal growth was found at 50%, with an average inhibition zone diameter of 20,85 mm at 24 hours and 14,68 mm at 48 hours of observation. These findings suggest the potential of white galangal extract as a fungistatic antifungal agent for treating tinea pedis. These results align with previous studies suggesting that an increase in extract concentration results in a larger inhibition zone size.

Item Type: Thesis (Skripsi)
Additional Information: [No. Panggil: 2010211031] [Pembimbing 1: Fajriati Zulfa] [Pembimbing 2: Agneta Irmarahayu] [Penguji: Citra Ayu Apriia]
Uncontrolled Keywords: Epidermophyton floccosum, tinea pedis, white galangal rhizome extract
Subjects: R Medicine > R Medicine (General)
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: Fathia Kharitano
Date Deposited: 07 Mar 2024 07:22
Last Modified: 07 Mar 2024 07:22
URI: http://repository.upnvj.ac.id/id/eprint/27952

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