PENGARUH PERBEDAAN FREKUENSI ULTRASOUND ASSISTED EXTRACTION (UAE) TERHADAP EFEKTIVITAS DAUN UNGU (GRAPTHOPHYLLUM PICTUM (L.) GRIFF) DALAM MENGHAMBAT PERRTUMBUHAN BAKTERI ESCHERICHIA COLI

Sabina Oktavia, . (2024) PENGARUH PERBEDAAN FREKUENSI ULTRASOUND ASSISTED EXTRACTION (UAE) TERHADAP EFEKTIVITAS DAUN UNGU (GRAPTHOPHYLLUM PICTUM (L.) GRIFF) DALAM MENGHAMBAT PERRTUMBUHAN BAKTERI ESCHERICHIA COLI. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

	Text ABSTRAK.pdf Download (90kB)
	Text AWAL.pdf Download (405kB)
	Text BAB 1.pdf Restricted to Repository UPNVJ Only Download (109kB) | Request a copy
	Text BAB 2.pdf Restricted to Repository UPNVJ Only Download (4MB) | Request a copy
	Text BAB 3.pdf Restricted to Repository UPNVJ Only Download (299kB) | Request a copy
	Text BAB 4.pdf Restricted to Repository UPNVJ Only Download (330kB) | Request a copy
	Text BAB 5.pdf Download (142kB)
	Text DAFTAR PUSTAKA.pdf Download (181kB)
	Text RIWAYAT HIDUP.pdf Restricted to Repository UPNVJ Only Download (123kB) | Request a copy
	Text LAMPIRAN.pdf Restricted to Repository UPNVJ Only Download (8MB) | Request a copy
	Text HASIL PLAGIARISME.pdf Restricted to Repository staff only Download (1MB) | Request a copy
	Text ARTIKEL.pdf Restricted to Repository staff only Download (530kB) | Request a copy

Abstract

Escherichia coli is a Gram-negative bacteria and is the main suspect for urinary tract infections and gastroenteritis. The cases of antibiotic resistance against E. coli continues to increase due to public non-compliance with taking antibiotics. Purple leaf (Graptophyllum pictum (L.) Griff) is a plant that grows widely in Indonesia and is generally used as a herbal medicine. This plant contains alkaloids, flavonoids, tannins and steroids which can inhibit bacterial growth. This content is obtained through an extraction process. The aim of this study was to determine the difference in effectiveness of purple leaves extracted using the Ultrasound Assisted Extraction method at a frequencies of 30 kHz, 40 kHz, and 50 kHz against the growth of E. coli. The antibacterial activity test used the well diffusion method, then the diameter of the inhibition zone was measured. This data was analyzed using the Kruskal-Wallis test and the Mann-Whitney test which resulted in significant differences between treatment groups. The average diameter of the inhibition zone produced at frequencies of 30 kHz, 40 kHz, and 50 kHz is respectively 3,40 mm; 6,22mm; 4,37mm. The results of this research show that the most optimal frequency is 40 kHz, this frequency is able to form cavitation in purple leaf cells, thereby producing phytochemical substances which have the ability to damage the cell structure of E. coli.

Item Type:	Thesis (Skripsi)
Additional Information:	[No. Panggil: 2010211133] [Pembimbing 1: Meiskha Bahar] [Pembimbing 2: Sri Wahyuningsih] [Penguji: Fajriati Zulfa]
Uncontrolled Keywords:	Antibacteria, Escherichia coli, Purple leaves, Ultrasound Assisted Extraction.
Subjects:	R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User:	Sabina Oktavia
Date Deposited:	20 Mar 2024 21:43
Last Modified:	20 Mar 2024 21:43
URI:	http://repository.upnvj.ac.id/id/eprint/28392

Actions (login required)

View Item