UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOL 50% KAYU SECANG (Caesalpinia sappan L.) TERHADAP JAMUR Candida albicans MENGGUNAKAN METODE DILUSI

Fairuz Zahra, . (2025) UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOL 50% KAYU SECANG (Caesalpinia sappan L.) TERHADAP JAMUR Candida albicans MENGGUNAKAN METODE DILUSI. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Frequent opportunistic fungal infections, including those caused by Candida species, remain a health issue that requires big attention from people. Tradionally, people have used secang as traditional medicine as an antifungal agent. This research seeks to assess the antifungal properties of secang wood extract using 50% ethanol as a solvent against the growth of C. albicans with the dilution method, as well as to examine the TFC involved in its antifungan effect. The second metabolism contents in the extract suspected to contribute to antifungal activity include flavonoids, alkaloids, saponins, tannins, terpenoids, and phenolics. The MIC was observed at an extract concentration of 5000 ppm, while the MFC was only evident at concentrations above 5000 ppm. The amount of total flavonoid content in the extract, which was 28.57 mgQE/g, played a role in supporting the antifungal activity. Fisher's Exact Test revealed a correlation between the treatment groups and fungal growth based on MIC data, Welch ANOVA followed by the Post Hoc Games-Howell tests revealed notable differences between groups based on colony data in the MFC test (Sig<0.05).

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 2110212017] [Pembimbing: Dhigna Luthfiyani Citra Pradana] [Penguji 1: Annisa Farida Muti] [Penguji 2: Erna Harfiani]
Uncontrolled Keywords: Antifungal Activity, Candida albicans, Dilution, MFC, MIC
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QK Botany
Q Science > QR Microbiology
Divisions: Fakultas Kedokteran > Program Studi Farmasi (S1)
Depositing User: FAIRUZ ZAHRA
Date Deposited: 12 Aug 2025 01:31
Last Modified: 12 Aug 2025 01:31
URI: http://repository.upnvj.ac.id/id/eprint/38456

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