THE IMPACT OF ORAL MATERNAL COLOSTRUM ADMINISTRATION ON THE IMMUNE SYSTEM OF PREMATURE BABIES

Adinda Alfi Azizah, . (2024) THE IMPACT OF ORAL MATERNAL COLOSTRUM ADMINISTRATION ON THE IMMUNE SYSTEM OF PREMATURE BABIES. The Impact of Oral Maternal Colostrum Administration on the Immune System of Premature Babies, 05 (04). pp. 763-772. ISSN 2721-1215

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Abstract

In children under five years of age, premature complications are now the second leading cause of death. Colostrum has important benefits in promoting the maturity of premature infants’ organ function dan preventing infections. Preterm infants are recommended to be given colostrum orally and pharyngeally as early as possible after birth to provide immune protective effects for their bodies. However, the stucking and swallowing function of preterm infants are often not optima;, partly due to comotbidities, which poses a significant challenge. As a result, the immune system of preterm infants is often low. This literature review aimed to evaluate the effect of oropharyngeal colostrum feeding through subgroup analysis based on complications. Descriptive research was conducted in April-June 2024 using the literature review method with PRISMA guidelines for RCTs. Literature sources were obtained from Pubmed (MEDLINE), Science Direct, Google Scholar, and Cochrane Library with a publication limit of the last ten years (2014-2023). Of the 1,657 result, 13 articles met the criteria. A total of 1,451 preterm infants were included in the 13 RCT studies. Result showed a lower incidence of late-onset sepsis and Necrotizing Enterocolitis (NEC) in the group that received oropharyngeal colostrum. In addition, oropharyngeal colostrum feeding accelerated the time to enteral feeding in preterm infants, ranging from 1-3 days in the intervention group and 4-7 days in the control group. The administration of oropharyngeal colostrum was shown to have a positive impact on the development and defense of the immune system of preterm infants, reduce helath problems such as sepsis and NEC, accelerate the recovery of birth weight, and reduce the incidence of mortality.

Item Type:	Article
Additional Information:	[No. Panggil: 2110714002] [Pembimbing: Yessi Crosita Octaria] [Penguji 1: Firlia Ayu Arini]
Uncontrolled Keywords:	Colostrum, Oropharyngeal, Immune System, Preterm Birth, Randomized Control Trial
Subjects:	R Medicine > RJ Pediatrics R Medicine > RM Therapeutics. Pharmacology
Divisions:	Fakultas Ilmu Kesehatan > Program Studi Gizi (S1)
Depositing User:	ADINDA ALFI AZIZAH
Date Deposited:	06 Aug 2025 01:21
Last Modified:	06 Aug 2025 01:21
URI:	http://repository.upnvj.ac.id/id/eprint/37235

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