AKTIVITAS ANTIBAKTERI EKSTRAK DAUN UNGU (GRAPTOPHYLLUM PICTUM (L.) GRIFF) TERHADAP BAKTERI STREPTOCOCCUS PNEUMONIAE DAN KLEBSIELLA PNNEUMONIAE

Dhafin Lingga Achadiono, . (2024) AKTIVITAS ANTIBAKTERI EKSTRAK DAUN UNGU (GRAPTOPHYLLUM PICTUM (L.) GRIFF) TERHADAP BAKTERI STREPTOCOCCUS PNEUMONIAE DAN KLEBSIELLA PNNEUMONIAE. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Stroke-associated pneumonia is a common stroke complication caused by bacterial infections with an increased risk of antimicrobial resistance organism infection in elderly patients through prophylactic use of antimicrobial agents. As such, herbal drug alternatives are needed to eradicate the incidence of antimicrobial resistance infections. Graptophyllum pictum (L.) Griff (Purple leaf) has been shown to have antimicrobial properties through disrupting bacteria replication and metabolism. This research was conducted to observe the antimicrobial activity of G. pictum extract on Streptococcus pneumoniae and Klebsiella pneumoniae. This research was a true experimental research model using 3,12 ppm; 6,25 ppm; 12,5 ppm; 25 ppm; 50 ppm; 100 ppm of G. pictum (Purple leaf) extracts concentrations, Minimum inhibitory concentration, minimum bactericidal concentration, and zone of inhibition formation was observed through the microdilution and disc diffusion method on S. pneumoniae and K. pneumoniae growth. The data was analyzed to determine the mean difference of each concentration and the result difference between the two groups Based on the research results, it was found that G. pictum (Purple leaf) extract has a strong antibacterial effect on 100 ppm concentration, an intermediate antibacterial effect on 50 ppm and 25 ppm, and weak antibacterial effect on 3,12 ppm concentration against S. pneumoniae. In testing against K. pneumoniae bacteria, no antibacterial activity was found in all tested concentrations. concentration

Item Type: Thesis (Skripsi)
Additional Information: [No. panggil : 2010211056] [Pembimbing 1 : Feda Anisah Makkiyah] [Pembimbing 2 : Tri Faranita] [Penguji : Meiskha Bahar]
Uncontrolled Keywords: Caricature plant, Graptophyllum pictum, Antibacterial Activity, Streptococcus pneumoniae, Klebsiella pneumoniae
Subjects: Q Science > QR Microbiology
R Medicine > R Medicine (General)
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: DHAFIN LINGGA ACHADIONO
Date Deposited: 04 Oct 2024 03:59
Last Modified: 04 Oct 2024 04:01
URI: http://repository.upnvj.ac.id/id/eprint/30970

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