COST EFFECTIVENESS ANALYSIS ANTIBIOTIK SEFTRIAKSON DAN LEVOFLOKSASIN PADA PASIEN DEWASA DEMAM TIFOID RAWAT INAP DI RSPAD GATOT SOEBROTO

Thelma Meutia Salsabila Zaputra, . (2023) COST EFFECTIVENESS ANALYSIS ANTIBIOTIK SEFTRIAKSON DAN LEVOFLOKSASIN PADA PASIEN DEWASA DEMAM TIFOID RAWAT INAP DI RSPAD GATOT SOEBROTO. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Typhoid fever is an acute systemic infectious disease caused by Salmonella typhi infection which is still a concern in Indonesia as an endemic area for typhoid fever. Ceftriaxone and levofloxacin are now the drug of choice of typhoid fever due to resistance to first-line antibiotics. The choice of antibiotics is a factor that affects the cost of treatment. The aims of this study was to determine the cost-effectiveness of ceftriaxone and levofloxacin which were given to adult patients who were diagnosed with typhoid fever in Gatot Soebroto Army Hospital based on length of stay and total direct medical cost. This study is an observational analytical with a cross sectional design. The data was taken from the medical records and billing records including demographic data, length of stay, type of antibiotics used and direct medical costs from 48 samples who met the inclusion and exclusion criteria through purposive sampling technique. The results showed that levofloxacin was more cost-effective than ceftriaxone based on the cost-effectiveness grid placement with an ACER value of levofloxacin of Rp 1,259,402 with a length of hospitalization of 4.43 days and an ACER value of ceftriaxone of Rp 1,243,491 with a length of hospitalization of 5.35 days. The results of ACER analysis of levofloxacin have better effectiveness with minimal cost compared to ceftriaxone. The conclusion of this study is that levofloxacin is more cost-effective than ceftriaxone in treatment of typhoid fever

Item Type:	Thesis (Skripsi)
Additional Information:	[No.Panggil: 2010211088] [Pembimbing 1: Yanti Harjono Hadiwiardjo] [Pembimbing 2 : Marlina Dewiastuti] [Penguji : Hany Yusmaini]
Uncontrolled Keywords:	cost effectiveness analysis, ceftriaxone, levofloxacin, typhoid fever
Subjects:	R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User:	Thelma Meutia Salsabila Zaputra
Date Deposited:	15 Mar 2024 02:32
Last Modified:	15 Mar 2024 02:32
URI:	http://repository.upnvj.ac.id/id/eprint/27886

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