PERBANDINGAN EFEKTIVITAS STATIN DAN NON STATIN DALAM MANAJEMEN DISLIPIDEMIA PADA PASIEN PENYAKIT JANTUNG KORONER DI RUMAH SAKIT UMUM PUSAT PERSAHABATAN

Muhammad Bintang Buono, . (2026) PERBANDINGAN EFEKTIVITAS STATIN DAN NON STATIN DALAM MANAJEMEN DISLIPIDEMIA PADA PASIEN PENYAKIT JANTUNG KORONER DI RUMAH SAKIT UMUM PUSAT PERSAHABATAN. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Coronary heart disease (CHD) remains a leading cause of global morbidity and mortality, with dyslipidemia serving as a major determinant of atherosclerotic progression. Dyslipidemia is characterized by elevated levels of total cholesterol, triglycerides, and LDL cholesterol, along with reduced HDL cholesterol. Both statin and non-statin therapies are utilized in the management of dyslipidemia; however, comparative evidence regarding their effectiveness in CHD populations remains inconsistent. This study aimed to compare the effectiveness of statin and non-statin therapy on lipid profile improvement among CHD patients. An analytical observational study with a cross-sectional design was conducted using medical record data of CHD patients with dyslipidemia at RSUP Persahabatan in 2024. A total of 124 patients met the inclusion criteria. Most patients were elderly (60.5%), female (52%), and classified as overweight based on body mass index (46%). Statins were prescribed to 73% of patients, whereas non-statins were used by 27%. The Mann–Whitney test demonstrated significant differences in LDL levels (p = 0.002), triglycerides (p = 0.001), and total cholesterol (p = 0.036), while no significant difference was observed in HDL levels (p = 0.675). The study concludes that statins are more effective in reducing LDL levels and increasing HDL levels, whereas non-statin therapy shows greater effectiveness in lowering triglycerides and total cholesterol.

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 2210211121] [Pembimbing 1: Citra Ayu Aprilia] [Pembimbing 2: Tiwuk Susantiningsih] [Penguji : Hanny Yusmaini]
Uncontrolled Keywords: Coronary Heart Disease, Dyslipidemia, Lipid Profile, Non-statins, Statins
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: MUHAMMAD BINTANG BUONO
Date Deposited: 30 Apr 2026 03:24
Last Modified: 30 Apr 2026 03:24
URI: http://repository.upnvj.ac.id/id/eprint/41334

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