PENGARUH PEMBERIAN EKSTRAK BONGGOL NANAS (ANANAS COMOSUS (L.) MERR.) TERHADAP MORFOLOGI SPERMATOZOA TIKUS DIABETIK GALUR WISTAR (RATTUS NORVEGICUS) YANG DIINDUKSI ALOKSAN

Ratu Salwa Khairunnisa, . (2026) PENGARUH PEMBERIAN EKSTRAK BONGGOL NANAS (ANANAS COMOSUS (L.) MERR.) TERHADAP MORFOLOGI SPERMATOZOA TIKUS DIABETIK GALUR WISTAR (RATTUS NORVEGICUS) YANG DIINDUKSI ALOKSAN. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Diabetes mellitus triggers oxidative stress, leading to impaired sperm morphology. Pineapple core extract (Ananas comosus (L.) Merr.), rich in flavonoids, saponins, and tannins, possesses antioxidant properties that may support cellular regeneration. This study aimed to evaluate the effect of pineapple core extract on sperm morphology in alloxan-induced diabetic male Wistar rats. An experimental post-test only control group design was applied across five groups, including negative control, positive control, and three treatment groups (50%, 75%, and 100% concentrations). Statistical analysis utilized Shapiro-Wilk and Kruskal-Wallis tests. The results demonstrated a descriptive increase in normal sperm morphology across all treatment groups compared to the positive control, although the improvement was not statistically significant (p > 0,05). In conclusion, pineapple core extract, especially at 100% concentration, shows descriptive potential in supporting the restoration of sperm morphology under diabetic conditions.

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 2210211142] [Penguji: Nasihin Saud Irsyad] [Pembimbing 1: Cut Fauziah] [Pembimbing 2: Taufiq Fredrik Pasiak]
Uncontrolled Keywords: Keywords: alox, pineapple hump, diabetes mellitus, spermatozoa morphology, Wistar rat
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: RATU SALWA KHAIRUNNISA
Date Deposited: 16 Apr 2026 02:24
Last Modified: 16 Apr 2026 02:24
URI: http://repository.upnvj.ac.id/id/eprint/41219

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