HUBUNGAN KANKER TIROID PAPILER DAN KADAR TSH TERHADAP SKOR AMES UNTUK MENENTUKAN PROGNOSIS DI RSPAD GATOT SOEBROTO PERIODE JANUARI 2023 - JULI 2024

Andi Zahirah Andifa, . (2024) HUBUNGAN KANKER TIROID PAPILER DAN KADAR TSH TERHADAP SKOR AMES UNTUK MENENTUKAN PROGNOSIS DI RSPAD GATOT SOEBROTO PERIODE JANUARI 2023 - JULI 2024. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

ABSTRACT Objective: Thyroid cancer is the most common endocrine malignancy, with a globally increasing incidence, particularly among women and individuals aged 15-39 years. In Indonesia, thyroid cancer ranks fifth among women, with more than 13,100 new cases reported in 2020, accounting for 3.3% of total cancer cases. The prognosis of thyroid cancer is influenced by factors such as histological type, age, disease stage, and thyroid-stimulating hormone (TSH) levels, though the relationship between TSH levels and prognosis remains a topic of ongoing research. The AMES score (Age, Metastasis, Extent, Size) is a prognostic tool used to classify patients into low-risk or high-risk categories. However, regarding the relationship between thyroid cancer type and TSH levels, has not been widely studied. This research aims to investigate the relationship between thyroid cancer type and TSH levels in predicting patient prognosis using the AMES score. Methods: This analytic observational research using a case-control design conducted on thyroid carcinoma papillary patients at Gatot Soebroto Army Central Hospital from January 2023 to July 2024. The study includes data from 45 patients, and the data analysis was performed using the Chi-Square test and the Exact test. Results: The results of the study showed that the majority of papillary thyroid cancer variants were of the follicular type (40%). Most patients had normal TSH levels (51,1%). The majority of patients were classified into the high-risk group based on the AMES score (51,1%). Statistical analysis revealed significant relationship between the type of papillary thyroid cancer and the AMES score based on the Exact test (p = 0,032). Additionally, no significant relationship was found between TSH levels and the AMES score based on the Chi-Square test (p = 0,295). Conclusion: There was significant relationship between the type of papillary thyroid cancer with the AMES score and no significant relationship between TSH with AMES score. Keywords : AMES, Cancer, Hospital, Thyroid, TSH

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil : 2110211105] [Pembimbing 1 : Retno Yulianti] [Pembimbing 2 : Tri Faranita] [Pembimbing 3 : Karina]
Uncontrolled Keywords: AMES, Cancer, Hospital, Thyroid, TSH
Subjects: R Medicine > RB Pathology
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: ANDI ZAHIRAH ANDIFA
Date Deposited: 25 Mar 2025 07:44
Last Modified: 25 Mar 2025 07:44
URI: http://repository.upnvj.ac.id/id/eprint/34809

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