Yubella Ratna Feirani, . (2024) ANALISIS PERBEDAAN MARKA GEN PENUAAN MMP-9 PADA RNA SEL FIBROBLAS YANG DIINDUKSI ULTRAVIOLET B. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
Background: Aging is a time-dependent decline in organ function. Both external and internal factors contribute to aging. Matrix metalloproteinase 9 is one of the complex proteolytic metalloenzymes that plays a role in the degradation of the extracellular matrix in the skin and other organs. Ultraviolet B is one of the ultraviolets that can accelerate aging. Humans are often exposed to ultraviolet B rays through sunlight. Method: The study was conducted with an experimental research design, true experimental using a posttest-only control design. The data obtained were then processed using SPSS with the Shapiro Wilk normality test and the ANOVA test. Significant results if the p-value <0.05 is obtained. Results: The results of the ANOVA test showed a Sig value <0.05. Thus, the results were increased but statistically not significant. Conclusion: There was an increase in the MMP-9 aging gene marker which was statistically insignificant in the RNA of fibroblast cells that were not induced by UVB and induced by UVB in exposure times of 24 minutes, 48 minutes, and 96 minutes.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil: 2110211053] [Pembimbing: Karina] [Penguji 1: Mila Citrawati] [Penguji 2: Abdul Kolib] |
| Uncontrolled Keywords: | Matrix metalloproteinase 9, aging, ultraviolet B |
| Subjects: | R Medicine > RD Surgery |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | YUBELLA RATNA FEIRANI |
| Date Deposited: | 07 Mar 2025 07:13 |
| Last Modified: | 07 Mar 2025 07:13 |
| URI: | http://repository.upnvj.ac.id/id/eprint/34222 |
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