HUBUNGAN LAMA PENGGUNAAN DUAL ANTI-PLATELET THERAPY DENGAN KEJADIAN MAJOR ADVERSE CARDIOVASCULAR EVENTS PADA PASIEN PASCA SINDROM KORONER AKUT DI RS BHAYANGKARA TINGKAT I PUSDOKKES POLRI

Nur Aliah Muhammad Idrus Ba'agil, . (2024) HUBUNGAN LAMA PENGGUNAAN DUAL ANTI-PLATELET THERAPY DENGAN KEJADIAN MAJOR ADVERSE CARDIOVASCULAR EVENTS PADA PASIEN PASCA SINDROM KORONER AKUT DI RS BHAYANGKARA TINGKAT I PUSDOKKES POLRI. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Introduction: Acute Coronary Syndrome (ACS) remains one of the top ten non-communicable diseases causing the highest mortality in Indonesia. The standard management recommended by the Indonesian Heart Association for post-ACS patients to prevent Major Adverse Cardiovascular Events (MACE) is Dual Antiplatelet Therapy (DAPT) for 12 months,Despite of the optimal duration of DAPT use for reducing MACE risk is still controversial. This study analyzed the relationship between DAPT duration and MACE incidence in post-ACS patients at First Level Of Bhayangkara Pusdokkes POLRI Hospital. Methods: This was an analytical observational study using a cross-sectional design on post-ACS patients at First Level Of Bhayangkara Pusdokkes POLRI Hospital from 2022-2023. We identified 100 patients who used divided in two groups of DAPT duration: 6 months and 12 months, with ages <65 years. Data analysis used McNemar test. Results: Among the 100 patients analyzed, Most patients were 40-60 years old (57%). The majority were male (72%), with the most common Body Mass Index (BMI) category being Class 1 obesity (42%). (22%) of patients were classified as prehypertensive, and (24%) had dyslipidemia. MACE events among post-ACS patients included myocardial infarction (28%), stroke (1%), and death (1%). After 6 months of therapy, 51 patients (51%) experienced MACE, while after 12 months, only 29 patients (29%) experienced MACE. It was found that there was a significant correlation between the duration of DAPT and the incidence of MACE (p=0.004). Conclusion: There was a significant correlation between the duration of DAPT and the incidence of MACE.

Item Type: Thesis (Skripsi)
Additional Information: [No. Panggil: 2110211099] [Pembimbing 1: Citra Ayu Aprilia] [Pembimbing 2: Tri Faranita] [Penguji: Hany Yusmaini]
Uncontrolled Keywords: Acute Coronary Syndrome, Dual Anti-platelet Therapy, Major Adverse Cardiovascular Events.
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: NUR ALIAH MUHAMMAD IDRUS BA'AGIL
Date Deposited: 17 Mar 2025 01:40
Last Modified: 17 Mar 2025 01:40
URI: http://repository.upnvj.ac.id/id/eprint/34156

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