Rasya Thahirah, . (2024) FORMULASI DAN UJI IRITASI SEDIAAN ESSENCE EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) DENGAN BERBAGAI VARIASI KONSENTRASI. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
Soursop leaves (Annona muricata L.) contain a relatively high amount of phenolic compounds. This study aims to formulate an essence preparation of soursop leaf ethanol extract and conduct tests on the physical properties of the preparation, irritation tests, and total phenolic content tests. The extract was obtained using the ultrasonic method, then formulated into essence preparations with varying concentrations of soursop leaf ethanol extract, namely F0 (negative control), F1 (2%), F2 (4%), and F3 (6%). The physical properties of the preparations were tested, including organoleptic tests; pH tests; homogeneity tests; spreading tests; viscosity tests; irritation tests, and total phenolic content tests. The formulations of soursop leaf extract essence F1 (2%), F2 (4%), and F3 (6%) exhibited good physical quality, increased total phenolic content with higher extract concentrations, and did not cause irritation. This study indicates that the soursop leaf ethanol extract essence preparation F3 (6% extract) is the best formula meeting standards, with brown color, characteristic smell of cocoa beans, liquid texture; pH 5.50 ± 0.1; homogeneous; spreading power of 7.33 ± 0.15 cm; viscosity of 707.18 ± 29.04 cP; non-irritating; and total phenolic content of 76.87 ± 0.01 mg GAE/g. The variation in extract concentration affects the pH, spreading power, viscosity, and total phenolic content of the soursop leaf ethanol extract essence preparations with a significance value of 0.000 (<0.05).
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil: 2010212050] [Pembimbing: Rika Revina] [Penguji 1: Annisa Farida Muti] [Penguji : Via Rifkia] |
| Uncontrolled Keywords: | Annona muricata L., Essence, Physical Properties Test, Irritation Test, Total Phenolic Content Test |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry Q Science > QK Botany Q Science > QL Zoology T Technology > TP Chemical technology |
| Divisions: | Fakultas Kedokteran > Program Studi Farmasi (S1) |
| Depositing User: | RASYA THAHIRAH |
| Date Deposited: | 09 Sep 2024 03:34 |
| Last Modified: | 09 Sep 2024 03:34 |
| URI: | http://repository.upnvj.ac.id/id/eprint/32994 |
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