ANALISIS INTERAKSI OBAT ANTITUBERKULOSIS – OBAT HIPOGLIKEMIK ORAL PADA PASIEN TUBERKULOSIS DI RSUP PERSAHABATAN TAHUN 2023

Nathasa Fabila Andrina, . (2024) ANALISIS INTERAKSI OBAT ANTITUBERKULOSIS – OBAT HIPOGLIKEMIK ORAL PADA PASIEN TUBERKULOSIS DI RSUP PERSAHABATAN TAHUN 2023. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and remains a significant global health issue. Managing TB treatment in patients with Diabetes Mellitus (DM) is particularly challenging due to the need to carefully consider interactions between anti-TB drugs (OAT) and oral hypoglycemic agents (OHO). This study aims to explore the impact of actual and potential interactions between Fixed-Dose Combination (FDC) OAT and OHO on treatment outcomes among newly diagnosed TB patients with type 2 DM, based on laboratory data including HbA1c, Fasting Blood Glucose (FBG), and Acid-Fast Bacilli (AFB) at RSUP Persahabatan in 2023. Conducted from January to May 2024 using a cross- sectional study design, the research involved 63 medical records meeting study criteria. Hypothesis testing utilized chi-square analysis. The majority of TB-DM patients at RSUP Persahabatan in 2023 were aged 45-59 years, female, and received FDC OAT. Statistical analysis indicated a significant association between OAT-OHO drug interactions and DM type 2 patient outcomes (p = 0.0001), with no significant relationship found for TB treatment outcomes.

Item Type: Thesis (Skripsi)
Additional Information: {No. Panggil: 2010212016} {Pembimbing 1: Dhigna Luthfiyana C,P.} {Pembimbing 2: Ima Maria} {Penguji: Annisa Farida Muti}
Uncontrolled Keywords: Pulmonary tuberculosis, Drugs Interaction, Acid-Fast Bacilli (AFB), , Fasting Blood Glucose (FBG), HbA1c
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Kedokteran > Program Studi Farmasi (S1)
Depositing User: NATHASA FABILA ANDRINA
Date Deposited: 06 Sep 2024 04:01
Last Modified: 06 Sep 2024 04:01
URI: http://repository.upnvj.ac.id/id/eprint/32017

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