HUBUNGAN RIWAYAT KELUARGA DAN PENGGUNAAN KONTRASEPSI HORMOANAL PADA KEJADIAN KANKER PAYUDARA DI RSPAD GATOT SOEBROTO TAHUN 2022

Khairunnisa Nur Erya, . (2024) HUBUNGAN RIWAYAT KELUARGA DAN PENGGUNAAN KONTRASEPSI HORMOANAL PADA KEJADIAN KANKER PAYUDARA DI RSPAD GATOT SOEBROTO TAHUN 2022. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Abstract: Breast cancer is the most common type of cancer in Indonesia. Breast cancer ranks first and is the leading cause of cancer-related deaths. There are many factors that can increase the risk of breast cancer, such as age, family history of breast cancer, and a history of hormonal contraceptive use. This study aims to investigate the relationship between family history and the use of hormonal contraceptives in the occurrence of breast cancer. Methods: This research is an observational analytic study with a cross-sectional research design. The study sample consists of patients diagnosed with breast cancer in 2022 who visited RSPAD Gatot Soebroto Jakarta. The research data were processed with SPSS and analyzed using the chi-square test and fisher exact test. Results: In this study, 44.2% of patients were aged 51-60 years, 27.9% had a family history, 48.8% had a history of hormonal contraceptive use for >5 years, 95.3% had histopathology results of the no special type, and 72.1% had immunohistochemistry results of the Luminal type. Analysis results of the Fisher exact test found a relationship between a family history (p=0.010) and the occurrence of breast cancer, while the chi-square test found no relationship between a history of hormonal contraceptive use (p=0.736) and the occurrence of breast cancer. The conclusion of this research is that there is an association between a family history and the occurrence of breast cancer, while there is no association between a history of hormonal contraceptive use and the occurrence of breast cancer. Keywords: Breast Cancer, Family History, Hormonal Contraception Abstrak: Kanker payudara merupakan jenis kanker terbanyak di Indonesia kanker payudara. Kanker payudara menempati urutan pertama serta menjadi penyumbang kematian pertama akibat kanker. Terdapat banyak faktor yang dapat meningkatkan risiko terjadinya kanker payudara seperti usia, riwayat keluarga menderita kanker payudara dan riwayat penggunaan kontrasepsi hormonal. Penelitian ini bertujuan untuk mengetahui adakah hubungan riwayat keluarga dan riwayat penggunaan kontrasepsi hormonal pada kejadian kanker payudara. Penelitian ini merupakan penelitian analitik observasional dengan desain penelitian cross-sectional. Sampel penelitian ini adalah pasien terdiagnosis kanker payudara pada tahun 2022 yang berkunjung ke RSPAD Gatot Soebroto Jakarta. Data penelitian dianalisis menggunakan uji chi-square dan uji fisher exact. Penelitian ini menemukan hasil terdapat 44.2% pasien berusia 51-60 tahun, 27.9% pasien memiliki riwayat keluarga, 48.8% pasien memiliki riwayat penggunaan kontrasepsi hormonal selama >5 tahun, 95.3% pasien memiliki hasil histopatologi jenis no special type, dan 72.1% pasien memiliki hasil imunohistokimia jenis Luminal. Hasil uji Fisher exact menemukan hubungan riwayat keluarga (p=0.010) dengan kejadian kanker payudara dan hasil uji chi-square menemukan tidak terdapat hubungan riwayat penggunaan kontrasepsi hormonal (p=0.736) dengan kejadian kanker payudara. Kesimpulan pada penelitian ini menemukan hubungan riwayat keluarga dengan kejadian kanker payudara dan tidak terdapat hubungan riwayat penggunaan kontrasepsi hormonal dengan kejadian kanker payudara. Kata kunci: Kanker Payudara, Kontrasepsi Hormonal, Riwayat Keluarga

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 2010211136] [Pembimbing 1: Uswatun Hasanah] [Pembimbing 2: Abdul Kolib,] [Penguji: Niniek Hardini]
Uncontrolled Keywords: Kanker Payudara, Kontrasepsi Hormonal, Riwayat Keluarga
Subjects: Q Science > QH Natural history > QH426 Genetics
R Medicine > RC Internal medicine
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: Khairunnisa Nur Erya
Date Deposited: 09 Mar 2024 04:31
Last Modified: 09 Mar 2024 04:31
URI: http://repository.upnvj.ac.id/id/eprint/28287

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