Gusti Putu Cintia Prayascita, . (2026) PENGARUH PAJANAN MIKROPLASTIK POLIETILENA TERHADAP MORFOLOGI SPERMA TIKUS PUTIH (Rattus norvegicus) GALUR WISTAR. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
Microplastics have raised health concern due to their increasing presence in the environment and their potential accumulation in human tissues. Several studies have shown that microplastics may adversely affect sperm quality. This study aimed to determine the effect of polyethylene microplastics exposure on sperm morphology in Wistar rats (Rattus norvegicus). A true experimental study was conducted using a post-test only control group design. Twenty-eight male Wistar rats were divided into four groups: a negative control group (K1) and three treatment groups receiving oral microplastics at doses of 0.0375 mg/day (K2), 0.3 mg/day (K3), and 0.6 mg/day (K4) for 14 days. Sperm morphology was assessed using Giemsa staining. Daya analysis using Kruskal-Wallis test showed a statistically significant at p=0.003. Post hoc Mann-Whitney U test revealed significant differences between several treatment groups. In conclusion, polyethylene microplastics exposure can reduce normal sperm morphology in Wistar rats.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil: 2210211084] [Pembimbing 1: Nasihin Saud Irsyad, S.Si, M.Biomed] [Pembimbing 2: Diana Agustini Purwaningastuti, M.Biomed, AIFO-K] [Penguji: Yosha Putri Wahyuni, S.ST. M.Biomed] |
| Uncontrolled Keywords: | Male Infertility, Microplastics, Sperm Morphology, Polyethylene |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | GUSTI PUTU CINTIA PRAYASCITA |
| Date Deposited: | 08 Sep 2026 03:15 |
| Last Modified: | 08 Sep 2026 03:15 |
| URI: | http://repository.upnvj.ac.id/id/eprint/50745 |
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