UJI KARAKTERISTIK DAN UJI IRITASI EKSTRAK ETANOL 70% BRACT PACING PENTUL SEBAGAI BIOSURFAKTAN DALAM PEMBUATAN SEDIAAN SAMPO

Daniel William Putra Theopilus, . (2026) UJI KARAKTERISTIK DAN UJI IRITASI EKSTRAK ETANOL 70% BRACT PACING PENTUL SEBAGAI BIOSURFAKTAN DALAM PEMBUATAN SEDIAAN SAMPO. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Synthetic surfactants such as Sodium Lauryl Sulphate have the potential to irritate and negatively impact the environment. Therefore, biosurfactant as a natural alternative is needed for safety reasons. Button ginger is presumed to possess biosurfactant activity based on its saponin content. However, its characteristics as a biosurfactant have not yet been evaluated. This research aims to determine the characteristics of the 70% ethanol extract of button ginger as a biosurfactant and its potential application in shampoo. biosurfactant characteristics, shampoo formulation, physical examination and HET-CAM irritation test were assessed to determine. The result showed that the extract had a yield of 12,52%, total saponin content 65,63 ± 4,52%, organoleptic exhibited changed, mass density 1,105 ± 0,01, pH extract 4,15 ± 0,06, high solubilty in aquadest and low in ethanol, HLB value 9,77, index emulsification 50,02 ± 3,28%, protease activity 2,43 ± 0,05 U/mL, surface tension 40 - 50 dyne/cm with CMC value 0,5%. The results of the shampoo formulation evaluation showed a pH of 4,91 ± 0,01, viscoscity 7429 ± 0,94 cP, foam height 5,17 ± 0,29 cm, surface tension 35–40 dyne/cm with CMC value 1%. Both extract and shampoo no cause irritation (score 0). Statistical analysis showed no significant differences for most parameters (p > 0,05), except for the emulsification index and surface tension (p < 0,05). Overall, pacing pentul demonstrates effective, safe, and environmentally friendly biosurfactant potential for shampoo formulation.

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 21102120212] [Pembimbing: Rika Revina] [Penguji 1: Aulia Farkhani] [Penguji 2: Via Rifkia]
Uncontrolled Keywords: Biosurfactant, Costus woodsonii, HET-CAM irritation, HLB test, Shampoo
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Kedokteran > Program Studi Farmasi (S1)
Depositing User: DANIEL WILLIAM PUTRA THEOPILUS
Date Deposited: 14 Apr 2026 03:54
Last Modified: 14 Apr 2026 03:54
URI: http://repository.upnvj.ac.id/id/eprint/49982

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