Marisa Athifa, . (2026) PEMBERIAN KEMOTERAPI FOLFOX PADA PENDERITA ADENOKARSINOMA KOLOREKTAL YANG BELUM BERMETASTASIS DI KOLON KANAN DAN KOLON KIRI TERHADAP KEJADIAN PROGRESIVITAS DI RS KANKER DHARMAIS TAHUN 2023-2024. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
Colorectal cancer is a significant global health problem and continues to be a leading cause of cancer-related mortality. Differences in tumor location between the right colon and left colon are known to have distinct biological and clinical profiles, which can influence the response to systemic therapies such as the FOLFOX regimen. This study aims to analyze the association between right-sided and left-sided colon cancer locations and the incidence of disease progression in non-metastatic colorectal adenocarcinoma patients at Dharmais Cancer Hospital. This study employed a retrospective study design with a sample of 35 patients. Data were obtained through medical records, and progression was determined based on RECIST 1.1 criteria. Bivariate analysis revealed a significant association between tumor location and progression (p=0.011). Multivariate analysis showed that right-sided colon location was a dominant predictor of progression with an Odds Ratio (OR) of 21.37 (95% CI: 1.85–130.85). In conclusion, patients with right-sided colon adenocarcinoma have a significantly higher risk of progression following FOLFOX administration compared to those with left-sided colon cancer.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil : 2110211132] [Pembimbing 1 :Salman Paris Harahap] [Pembimbing 2 : Retno Yulianti] [Penguji : Niniek Hardini] |
| Uncontrolled Keywords: | Colorectal Adenocarcinoma, FOLFOX, Right Colon, Left Colon, Progression disease, RECIST 1.1 |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | MARISA ATHIFA |
| Date Deposited: | 01 Apr 2026 02:05 |
| Last Modified: | 01 Apr 2026 02:05 |
| URI: | http://repository.upnvj.ac.id/id/eprint/42436 |
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