Rania Refanessa Dalila Putri, . (2025) PERBANDINGAN PEMBERIAN ARV PADA PASIEN HIV/AIDS DENGAN DAN TANPA KOINFEKSI TB BERDASARKAN PARAMETER HEMATOLOGI DAN IMUNOLOGI DI RS PELNI. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
![[img]](http://repository.upnvj.ac.id/style/images/fileicons/text.png) |
Text
ABSTRAK.pdf Download (189kB) |
|
Text
AWAL.pdf Download (7MB) |
|
Text
BAB 1.pdf Restricted to Repository UPNVJ Only Download (260kB) |
|
Text
BAB 2.pdf Restricted to Repository UPNVJ Only Download (3MB) |
|
Text
BAB 3.pdf Restricted to Repository UPNVJ Only Download (517kB) |
|
Text
BAB 4.pdf Restricted to Repository UPNVJ Only Download (472kB) |
|
Text
BAB 5.pdf Download (282kB) |
|
Text
DAFTAR PUSTAKA.pdf Download (458kB) |
|
Text
RIWAYAT HIDUP.pdf Restricted to Repository UPNVJ Only Download (192kB) |
|
Text
LAMPIRAN.pdf Restricted to Repository UPNVJ Only Download (2MB) |
|
Text
HASIL PLAGIARISME.pdf Restricted to Repository staff only Download (26MB) |
|
Text
ARTIKEL KI.pdf Restricted to Repository staff only Download (273kB) |
Abstract
Background: HIV/AIDS remains a major global health challenge, with tuberculosis (TB) being the most common opportunistic infection. TB-HIV coinfection accelerates disease progression and worsens hematological and immunological parameters. Antiretroviral therapy (ARV) is essential for immune restoration, but evidence comparing its effects between HIV/AIDS patients with and without TB coinfection in Indonesia remains limited. Methods: A retrospective cross-sectional study was conducted using medical records of HIV/AIDS patients receiving ARV therapy at RS Pelni during 2022-2024. A total of 53 patients were included through total sampling method: 19 patients without TB coinfection and 34 patients with TB coinfection. Data on hemoglobin, platelets, total leukocytes, and CD4+ count were collected after six months of ARV therapy. Statistical analysis used independent t-test and Mann-Whitney U test depending on data distribution. Results: After six months of ARV therapy, patients without TB coinfection showed significantly higher hemoglobin levels compared to those with TB coinfection (p = 0.001). However, there were no significant differences in platelet count (p = 0.767), total leukocyte count (p = 0.897), or CD4+ count (p = 0.317) between the two groups. Conclusion: ARV therapy effectively improves hematological and immunological parameters in both HIV/AIDS patient groups. However, TB coinfection significantly hampers hemoglobin recovery after six months of therapy. These findings emphasize the need for enhanced monitoring and management strategies for HIV-TB coinfected patients.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No. Panggil: 2210211048] [Pembimbing 1: Erna Harfiani] [Pembimbing 2: Ima Maria] [Penguji: Hany Yusmaini] |
| Uncontrolled Keywords: | antiretroviral therapy, CD4+ count, hematological parameters, HIV/AIDS, immunological parameters, TB coinfection |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology R Medicine > RZ Other systems of medicine |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | RANIA REFANESSA DALILA PUTRI |
| Date Deposited: | 20 Apr 2026 04:59 |
| Last Modified: | 20 Apr 2026 04:59 |
| URI: | http://repository.upnvj.ac.id/id/eprint/41381 |
Actions (login required)
 |
View Item |