ANALISIS PENGARUH DURASI PEMBERIAN OBAT ANTIRETROVIRAL LINI I TERHADAP KADAR CD4+ PADA PASIEN DEWASA HIV DI RS PELNI JAKARTA TAHUN 2023-2024

Wyanda Puan Palarti Jubair Hegemur, . (2025) ANALISIS PENGARUH DURASI PEMBERIAN OBAT ANTIRETROVIRAL LINI I TERHADAP KADAR CD4+ PADA PASIEN DEWASA HIV DI RS PELNI JAKARTA TAHUN 2023-2024. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

HIV infection reduces the immune system through progressive damage to CD4+ cells, so medical personnel need to periodically evaluate the effectiveness of antiretroviral therapy (ART). The researchers aimed to analyze the effect of the duration of first-line ART on the increase in CD4+ levels in adult HIV patients during the 2023–2024 period. The researchers used an analytical observational study design with a cross-sectional approach. This study was conducted in August 2025 at Pelni Hospital by utilizing medical records of patients who had undergone ART for at least 6 months, selecting 50 data points through simple random sampling, and using univariate and bivariate analysis with the Wilcoxon test. The analysis results showed that the duration of first-line ART administration influenced the increase in CD4+ levels in adult patients, with an average of 256.88 cells/mm³ at 6 months and 335.78 cells/mm³ at 12 months. These findings confirm that the duration of first-line ARV administration plays an important role in the success of the immunological response in HIV patients and emphasize the need for continuous therapy monitoring.

Item Type: Thesis (Skripsi)
Additional Information: [No. Panggil: 2210211234] [Pembimbing 1: Erna Harfiani] [Pembimbing 2: Desi Purwaningsih] [Penguji: Citra Ayu Aprilia]
Uncontrolled Keywords: ARV, CD4, HIV, Immunology, Therapy
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: WYANDA PUAN PALARTI JUBAIR HEGEMUR
Date Deposited: 15 Apr 2026 07:53
Last Modified: 15 Apr 2026 07:53
URI: http://repository.upnvj.ac.id/id/eprint/40941

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