Febriana Fitrianingsih, . (2025) PENGARUH PEMBERIAN TERAPI OBAT ANTITUBERKULOSIS TERHADAP KADAR ENZIM TRANSAMINASE PASIEN TUBERKULOSIS PARU KOMORBID DIABETES MELITUS TIPE 2 DI RSUP PERSAHABATAN TAHUN 2024. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
![[img]](http://repository.upnvj.ac.id/style/images/fileicons/text.png) |
Text
ABSTRAK.pdf Download (195kB) |
|
Text
AWAL.pdf Download (570kB) |
|
Text
BAB I.pdf Restricted to Repository UPNVJ Only Download (237kB) |
|
Text
BAB II.pdf Restricted to Repository UPNVJ Only Download (600kB) |
|
Text
BAB III.pdf Restricted to Repository UPNVJ Only Download (319kB) |
|
Text
BAB IV.pdf Restricted to Repository UPNVJ Only Download (558kB) |
|
Text
BAB V.pdf Download (169kB) |
|
Text
DAFTAR PUSTAKA.pdf Download (322kB) |
|
Text
RIWAYAT HIDUP.pdf Restricted to Repository UPNVJ Only Download (113kB) |
|
Text
LAMPIRAN.pdf Restricted to Repository UPNVJ Only Download (702kB) |
|
Text
HASIL PLAGIARISME.pdf Restricted to Repository staff only Download (13MB) |
|
Text
ARTIKEL KI.pdf Restricted to Repository staff only Download (380kB) |
Abstract
Pulmonary tuberculosis (TB) is an infectious condition caused by the bacterium mycobacterium tuberculosis (M. tuberculosis). The prescribed treatment includes first-line antituberculosis drugs (ATD) such as isoniazid, rifampicin, and pyrazinamide. One notable side effect after a 6-month course of ATD therapy is hepatotoxicity. This study aimed to identify significant differences in transaminase enzyme levels before and after ATD treatment in pulmonary TB patients with concurrent type 2 diabetes mellitus (DM) at RSUP Persahabatan in 2024. Conducted retrospectively, the research utilized medical records from pulmonary TB patients with comorbid type 2 DM at RSUP Persahabatan during 2024. Recorded patient characteristics included age group and gender. The dependent variable was the level of transaminase enzymes after OAT administration, while the independent variable was the OAT administration itself. Among the 99 pulmonary TB patients with comorbid type 2 DM at RSUP Persahabatan in 2024, who met both inclusion and exclusion criteria, an increase in the average value of transaminase enzymes was observed following OAT therapy. A significant difference in transaminase enzyme levels (p<0.001) was found between pre- and post-OAT administration in these patients.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil: 2110212040] [Pembimbing: Dhigna Luthfiyani Citra Pradana] [Penguji 1: Annisa Farida Muti] [Penguji 2: Erna Harfiani] |
| Uncontrolled Keywords: | OAT, Pulmonary TB, Type 2 DM, Transaminase enzymes |
| Subjects: | Q Science > QP Physiology R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Kedokteran > Program Studi Farmasi (S1) |
| Depositing User: | FEBRIANA FITRIANINGSIH |
| Date Deposited: | 25 Aug 2025 03:59 |
| Last Modified: | 25 Aug 2025 03:59 |
| URI: | http://repository.upnvj.ac.id/id/eprint/38198 |
Actions (login required)
 |
View Item |