FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN WAKTU KONVERSI SPUTUM PADA PASIEN TUBERKULOSIS MULTIDRUG-RESISTANT DENGAN PADUAN ALL-ORAL DI RSUP PERSAHABATAN PERIODE 2021-2022

Sahat Anugerah Immanuel Sitinjak, . (2025) FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN WAKTU KONVERSI SPUTUM PADA PASIEN TUBERKULOSIS MULTIDRUG-RESISTANT DENGAN PADUAN ALL-ORAL DI RSUP PERSAHABATAN PERIODE 2021-2022. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Background: Multidrug-resistant tuberculosis (MDR-TB) presents challenges in achieving timely treatment success. Sputum conversion time, a key indicator of treatment progress, varies among patients and is influenced by demographic and clinical factors. This study examined factors associated with sputum conversion time in MDR-TB patients treated with all-oral regimens at Persahabatan Hospital from 2021 to 2022. Methods: A retrospective cohort study analyzed 154 MDR-TB patients categorized by sputum conversion time (≤2 months or >2 months). Independent variables included age, sex, diabetes mellitus, anemia, prior TB treatment, pulmonary cavitation, education level, marital status, and initial sputum AFB results. Patients with primary pulmonary MDR-TB confirmed via sputum culture, aged ≥18 years, and treated per Indonesian guidelines were included. Logistic regression identified significant factors. Results: Four factors significantly influenced sputum conversion time. Elderly age reduced the likelihood of delayed conversion, while anemia, pulmonary cavitation, and higher initial sputum AFB results were associated with prolonged conversion times. Conclusion: Anemia, pulmonary cavitation, and initial sputum results are risk factors for delayed sputum conversion, whereas elderly age is protective

Item Type: Thesis (Skripsi)
Additional Information: [No. Panggil: 2110211086] [Pembimbing 1: Erna Harfiani] [Pembimbing 2: Yanto Sandy Tjang] [Penguji: Hikmah Muktamiroh]
Uncontrolled Keywords: Drug Resistant, Risk Factors, Sputum Conversion, Tuberculosis
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: SAHAT ANUGERAH IMMANUEL SITINJAK
Date Deposited: 21 Mar 2025 04:30
Last Modified: 21 Mar 2025 04:30
URI: http://repository.upnvj.ac.id/id/eprint/34813

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