Naufal Rafi Kusuma Wibowo, . (2025) HUBUNGAN ANTARA PENANDA INFLAMASI DAN ELASTISITAS VASKULAR PADA MAHASISWA PREHIPERTENSI. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
Objective The study found that 34.7% of medical students experienced prehypertension. Prehypertension has the potential to trigger inflammation, which may subsequently reduce vascular elasticity. This study aims to investigate the relationship between inflammatory markers and vascular elasticity in prehypertensive medical students. Methods This study used a case-control design and a simple random sampling technique. The subjects' demographic characteristics were collected using a questionnaire. Vascular elasticity was measured using the Accelerated Photoplethysmograph (APG) Analyzer SA-3000P. Hematologic parameters were analyzed with the Hematology Analyzer Alinity HQ, while blood pressure was measured using a Digital Sfigmomanometer. The subjects comprised 27 prehypertensive subjects (cases) and 27 normotensive subjects (controls). Results The study found that 21 subjects (77.8%) had suboptimal vascular elasticity. A total of 21 subjects (77.8%) had a high neutrophil-to-lymphocyte ratio (NLR) value, and 19 subjects (70.4%) had a high-risk platelet-to-lymphocyte ratio (PLR) value. The Chi-square test indicated a significant relationship between the inflammatory marker NLR and vascular elasticity (p = 0.000; OR = 7.0; CI = 2.3-20.7). However, no relationship was found between PLR and vascular elasticity (p = 0.525). A significant relationship was also identified between vascular elasticity and prehypertension (p = 0.000; OR = 5.2; CI = 2.0-13.2). Conclusion Subjects with prehypertension exhibited NLR values that were seven times higher than those with normal blood pressure. Additionally, subjects with suboptimal vascular elasticity were 5.2 times more likely to develop prehypertension than those with normal or optimal vascular elasticity.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No. Panggil: 2110211080] [Pembimbing 1 : Nurfitri Bustamam] [Pembimbing 2: Meiskha Bahar] [Penguji : Diana Agustini Purwaningastuti] |
| Uncontrolled Keywords: | Medical Students, Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, Prehypertension, Vascular Elasticity. |
| Subjects: | Q Science > QP Physiology R Medicine > R Medicine (General) |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | NAUFAL RAFI KUSUMA WIBOWO |
| Date Deposited: | 27 Mar 2025 02:06 |
| Last Modified: | 27 Mar 2025 02:06 |
| URI: | http://repository.upnvj.ac.id/id/eprint/34559 |
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