Ardesta Edvantinus, . (2025) PERBANDINGAN PROFIL SEL IMUN DARI PBMC PASIEN KANKER KOLON TANPA RIWAYAT KEMOTERAPI DENGAN PROFIL SEL IMUN PASIEN NON KANKER DI KLINIK HAYANDRA TAHUN 2020–2022. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
![[img]](http://repository.upnvj.ac.id/style/images/fileicons/text.png) |
Text
ABSTRAK.pdf Download (308kB) |
|
Text
AWAL.pdf Download (1MB) |
|
Text
BAB 1.pdf Restricted to Repository UPNVJ Only Download (393kB) |
|
Text
BAB 2.pdf Restricted to Repository UPNVJ Only Download (646kB) |
|
Text
BAB 3.pdf Restricted to Repository UPNVJ Only Download (382kB) |
|
Text
BAB 4.pdf Restricted to Repository UPNVJ Only Download (426kB) |
|
Text
BAB 5.pdf Download (196kB) |
|
Text
DAFTAR PUSTAKA.pdf Download (321kB) |
|
Text
RIWAYAT HIDUP.pdf Restricted to Repository UPNVJ Only Download (127kB) |
|
Text
LAMPIRAN.pdf Restricted to Repository UPNVJ Only Download (795kB) |
|
Text
HASIL PLAGIARISME.pdf Restricted to Repository staff only Download (10MB) |
|
Text
ARTIKEL KI.pdf Restricted to Repository staff only Download (638kB) |
Abstract
Objective Cancer is a condition characterized by the abnormal and uncontrolled division of cells, which can spread to surrounding tissues. Colon cancer refers to cancer that occurs in the colon region. As we advance towards modern times, immune cell therapy (ICT) has emerged as a promising cancer treatment method. However, research demonstrating the use and benefits of ICT remains limited. This encourages for further studies at Hayandra Clinic, Jakarta. The purpose of this study is to compare the immune cell profiles from Peripheral Blood Mononuclear Cells (PBMCs) of colon cancer patients with no history of chemotherapy to those of non-cancer patients at Hayandra Clinic between 2020 and 2022. Methods This study employed an observational analytic method with a cross-sectional design, utilizing total sampling techniques on 48 medical records that met the study's restriction criteria. Data analysis was performed using the compare means independent-samples T-test statistical method. Results The results revealed that the highest average percentage of PBMC expression was found in CD3-/CD19- (52.14%) overall, CD3-/CD19- (53.39%) in the colorectal cancer patient group, and CD3-/CD19- (50.90%) in the non-cancer patient group. The average CD3+ expression from PBMCs in the colorectal cancer patient group was 32.37% and 35.58% in the non-cancer patient group. Statistical analysis using the compare means independent-samples T-test showed a p-value > 0.05. Conclusion There was no statistically significant difference between the immune cell profiles of PBMCs from colorectal cancer patients without a history of chemotherapy and those of non-cancer patients at Hayandra Clinic from 2020 to 2022. However, the average percentage of CD3+ expression from PBMCs was higher in the non-cancer group compared to the colorectal cancer group. Bibliography : 34 (2010 – 2024) Keywords : Peripheral Blood Mononuclear Cells (PBMC), colon cancer, Cluster of Differentiation (CD)
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil: 2010211045] [Pembimbing 1: Karina] [Pembimbing 2: Taufiq Fredrik Pasiak] [Penguji: Niniek Hardini] |
| Uncontrolled Keywords: | Peripheral Blood Mononuclear Cells (PBMC), colon cancer, Cluster of Differentiation (CD) |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) R Medicine > RZ Other systems of medicine |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | ARDESTA EDVANTINUS |
| Date Deposited: | 24 Mar 2025 02:05 |
| Last Modified: | 24 Mar 2025 02:05 |
| URI: | http://repository.upnvj.ac.id/id/eprint/34221 |
Actions (login required)
 |
View Item |