IDENTIFIKASI OBAT YANG BERPOTENSI NEFROTOKSIK PADA PASIEN GAGAL GINJAL KRONIK RAWAT INAP DI RSPAD GATOT SOEBROTO TAHUN 2023

Dwi Putri Enjelita Sipayung, . (2024) IDENTIFIKASI OBAT YANG BERPOTENSI NEFROTOKSIK PADA PASIEN GAGAL GINJAL KRONIK RAWAT INAP DI RSPAD GATOT SOEBROTO TAHUN 2023. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Chronic kidney disease is a kidney disorder characterized by structural and functional damage to the kidneys for more than three months. Chronic kidney disease patients receiving various therapies are at risk of nephrotoxic effects, which can affect the patient's quality of life. This study aims to identify therapeutic descriptions of the mechanisms of potentially nephrotoxic drugs. The study used a cross-sectional design with retrospective data from medical records of patients with chronic kidney disease who were hospitalized at Gatot Soebroto Army Hospital in 2023. The prevalence of potential nephrotoxicity in patients with chronic kidney disease who were hospitalized was 112 patients (65.12%). The prevalence of nephrotoxic potential was mostly found in male patients (55.81%), aged 19-59 years (59.30%), stage 4-5 (91.86%), and had ≤ 3 comorbidities (76.74 %). Potentially nephrotoxic drugs were PPIs (51.67%), Diuretics (17.78%), NSAIDs (11.67%), Antibiotics (7.22%), Antiplatelets (5%), Statins (3.89 %), Antihistamines (1.67%), Chemotherapy (0.56%), and Vitamin C (0.56%). Chi-square analysis showed a significant association between gender and the number of comorbidities with nephrotoxic potential, but there was no significant association between age and stage of chronic kidney disease with nephrotoxic potential.

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 2010212015] [Pembimbing 1: Annisa Farida Muti] [Pembimbing 2: Nurfitri Bustamam] [Penguji: Eldiza Puji Rahmi]
Uncontrolled Keywords: chronic kidney disease, nephrotoxic, medication
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Kedokteran > Program Studi Farmasi (S1)
Depositing User: DWI PUTRI ENJELITA SIPAYUNG
Date Deposited: 06 Sep 2024 07:59
Last Modified: 06 Sep 2024 07:59
URI: http://repository.upnvj.ac.id/id/eprint/31971

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