Yudivaniel Zihono, . (2023) EFEKTIVITAS METFORMIN TERHADAP PENURUNAN MORTALITAS PASIEN COVID-19 DENGAN KOMORBID DIABETES MELITUS TIPE 2 DI RSUP FATMAWATI TAHUN 2020 - 2021. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
COVID-19 (coronavirus disease 2019) is an infectious disease caused by the SARS-CoV-2 virus and was first identified in Wuhan, China. Compared to COVID-19 patients without comorbidity, COVID-19 patients with type 2 diabetes (T2DM) have a higher mortality rate. T2DM is a metabolic disease where the body experience glucose elevation. T2DM patients usually receive metformin as first-line treatment. However, metformin efficacy in reducing patients’ mortality rate still needs further analysis. This study’s objective was to analyze metformin effectiveness in reducing COVID-19 patients with T2DM mortality rate in Fatmawati General Hospital in 2020 – 2021. An analytic observational design with a retrospective cohort approach was used. Samples were acquired from hospitalized COVID-19 patients with T2DM medical records in Fatmawati General Hospital in 2020 – 2021, gathered using a purposive sampling technique, and analyzed using Chi Square test. A total of 137 samples (56 received metformin, 81 did not receive metformin) were included in this study. Mortality in samples that received metformin (19,6%) was lower than those that did not (38,3%). Chi Square test showed a p-value<0,05 (p = 0,020) with a risk ratio<1,000 (risk ratio = 0,513), showing a relation between metformin treatment and lower mortality rate in COVID-19 patients with T2DM. This study concluded that metformin treatment was significantly related to a lower mortality rate in COVID-19 patients with T2DM in Fatmawati General Hospital.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil: 1910211106] [Pembimbing: Hany Yusmaini] [Penguji 1: Uswatun Hasanah] [Penguji 2: Erna Harfiani] |
| Uncontrolled Keywords: | Comorbidity, COVID-19, Metformin, Mortality, Type 2 Diabetes Mellitus (T2DM) |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | Yudivaniel Zihono |
| Date Deposited: | 09 Sep 2023 13:21 |
| Last Modified: | 09 Sep 2023 13:21 |
| URI: | http://repository.upnvj.ac.id/id/eprint/24499 |
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