Hanna Rizqita, . (2023) HUBUNGAN LEUKOSIT SEMEN DAN MORFOLOGI SPERMA TERHADAP FRAGMENTASI DNA SPERMA LAKI-LAKI INFERTIL DI RSIA SAMMARIE BASRA TAHUN 2022. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
In comparison to non-infertile males, infertile males' sperms are more frequently found to have DNA fragmentation during examinations. Sperm DNA fragmentation (sDF) often occurs in cases of individuals with urogenital infections which are characterized by an increase in the number of seminal leukocytes and occurs in men with impaired spermiogenesis. Spermiogenesis involves the formation of sperm morphology and the packing of sperm DNA; therefore, disruptions in this process can result in aberrant morphology and increased sDF. This study aimed to determine the relationship between seminal leukocytes and sperm morphology on sperm DNA fragmentation. Methods: Data were collected from 53 patients with primary and secondary infertility who underwent semen analysis and sperm DNA fragmentation examination from January to December 2022 in SamMarie Basra Women's and Children's Hospital. Sperm Chromatin Dispersion (SCD) was used to evaluate sDF. The design of this study was crosssectional. Results: there was a significant correlation between sperm morphology and sDF (rs=-0.314, p<0.05), however, seminal leukocytes and sDF were not significantly correlated. Conclusion: An increase in normal sperm morphology, but not seminal leukocytes, can be associated with a decline in sperm DNA fragmentation.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No.Panggil: 1910211045] [Penguji 2/Pembimbing 1: Uswatun Hasanah] [Penguji 3/Pembimbing 2: Mila Citrawati] [Penguji 1: Karina] |
| Uncontrolled Keywords: | Sperm DNA Fragmentation, Infertility, Seminal Leukocyte, Sperm Morphology |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | Hanna Rizqita |
| Date Deposited: | 03 Mar 2023 08:07 |
| Last Modified: | 03 Mar 2023 08:07 |
| URI: | http://repository.upnvj.ac.id/id/eprint/23220 |
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