HUBUNGAN SINDROM METABOLIK DENGAN HITUNG JUMLAH CD4 PADA PASIEN HIV/AIDS DI RSPAD GATOT SOEBROTO PERIODE JANUARI–DESEMBER 2021

Maishariifa Isfahani Saptowati, . (2023) HUBUNGAN SINDROM METABOLIK DENGAN HITUNG JUMLAH CD4 PADA PASIEN HIV/AIDS DI RSPAD GATOT SOEBROTO PERIODE JANUARI–DESEMBER 2021. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.

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Abstract

Antiretroviral (ARV) therapy has improved the life expectancy of patients with HIV infection. Studies reported that there is a risk of metabolic syndrome among patients receiving ARV. CD4 can be used as an immunostimulatory marker that describes immune conditions in non-AIDS-related events such as metabolic syndrome. The purpose of this study is to analyze the correlation between metabolic syndrome and CD4 count in HIV/AIDS patients. A cross-sectional study was conducted using medical records of 31 HIV/AIDS patients who have received at least 6 months of ARV therapy in Gatot Soebroto Army Hospital, Indonesia. The diagnosis of metabolic syndrome was made based on International Diabetes Federation (IDF) 2006 criteria. Sociodemographic aspects, components of metabolic syndrome, and body mass index were evaluated. The results showed that the majority of patients were aged 36–45 years (48.4%), male (77.4%), and active working status (83.9%). The most frequently reported component of metabolic syndrome besides central obesity is low HDL-C (87.1%), followed by hypertriglyceridemia (71%), hyperglycemia (51.6%), and hypertension (38.7%). The most prevalent body mass index is in between 25–29,9 (54,8%) which indicates majority of patients belong to class I obesity. CD4 count ≥200 cells/mm3 was found in 92.9% of HIV patients with metabolic syndrome. Bivariate analysis showed a P value of 0.037 (<0.05) which confirms a significant association between metabolic syndrome and CD4 count. Effective monitoring and management are recommended for HIV-infected patients who present with metabolic syndrome criteria.

Item Type: Thesis (Skripsi)
Additional Information: [No.Panggil: 1910211127] [Pembimbing 1: Soroy Lardo] [Pembimbing 2: Maria Selvester Thadeus] [Penguji : Ayodya Heristyorini]
Uncontrolled Keywords: HIV/AIDS, ARV, Metabolic Syndrome, CD4
Subjects: R Medicine > RC Internal medicine
Divisions: Fakultas Kedokteran > Program Studi Kedokteran (S1)
Depositing User: Maishariifa Isfahani Saptowati
Date Deposited: 02 Mar 2023 07:50
Last Modified: 02 Mar 2023 07:50
URI: http://repository.upnvj.ac.id/id/eprint/22240

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