Muhammad Ariq Fiqih, . (2019) PENGARUH PEMBERIAN EKSTRAK DAN INFUSA DAUN KELOR (Moringa oleifera) TERHADAP AKTIVITAS ENZIM KATALASE HEPAR MENCIT (Mus musculus) OBESITAS YANG DIINDUKSI 2-NITROPROPANE. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
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Abstract
Hepatocellular cancer is caused by cell damage due to an imbalance between Reactive Oxygen Species (ROS) and antioxidants. Obesity and exposure to 2Nitropropane compounds can trigger an increase in ROS if not balanced with antioxidants, one of which is the catalase enzyme. This study aims to determine the effect of Moringa oleifera leaf extract and infusion as exogenous antioxidants on activity of the liver enzyme catalase in obese mice induced by 2-Nitropropane. This research method is an experiment using obese mice given leaf extract (4 mg/day) and infusion (40 mg/day) Moringa oleifera for 20 days, then induced 2Nitropropane (0.02 mL/day). The results showed a decrease in liver enzyme catalase activity in obese mice after being induced by 2-Nitropropane (1,404±0.261 U/mL) with a control group (3,275±0.630 U/mL). Based on the One Way ANOVA test results obtained a P value of 0.001 (P<0.05) there are differences activity of the liver catalase enzyme which was given leaf extract (0.960±0.555 U/mL) and leaf infusion (1,229±0.592 U/mL) with groups control (3,275±0.630 U/ml). In this study it can be concluded that there is an effect of Moringa leaf extract and infusion administration on the activity of liver enzyme catalase in obesity mice induced by 2-Nitropropane.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No Panggil : 1610211080] [Pembimbing : Tiwuk Susatiningsih] [Penguji : Hany Yusmaini] |
| Uncontrolled Keywords: | 2-Nitropropane, Catalase, Moringa oleifera Leaves, Obesity. |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | Deny Wahyudin |
| Date Deposited: | 05 Jul 2022 04:37 |
| Last Modified: | 05 Jul 2022 04:37 |
| URI: | http://repository.upnvj.ac.id/id/eprint/18216 |
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