Adinda Triany Putri, . (2021) GAMBARAN HISTOPATOLOGI TUBULUS SEMINIFERUS PADA MENCIT (Mus musculus) SETELAH PEMBERIAN ZINC DAN DIINDUKSI SIKLOFOSFAMID. Skripsi thesis, Universitas Pembangunan Nasional Veteran Jakarta.
![[img]](http://repository.upnvj.ac.id/style/images/fileicons/text.png) |
Text
ABSTRAK.pdf Download (568kB) |
|
Text
AWAL.pdf Download (2MB) |
|
Text
BAB 1.pdf Download (1MB) |
|
Text
BAB 2.pdf Restricted to Repository UPNVJ Only Download (4MB) |
|
Text
BAB 3.pdf Restricted to Repository UPNVJ Only Download (3MB) |
|
Text
BAB 4.pdf Restricted to Repository UPNVJ Only Download (4MB) |
|
Text
BAB 5.pdf Download (293kB) |
|
Text
DAFTAR PUSTAKA.pdf Download (1MB) |
|
Text
RIWAYAT HIDUP.pdf Restricted to Repository UPNVJ Only Download (132kB) |
|
Text
LAMPIRAN.pdf Restricted to Repository UPNVJ Only Download (2MB) |
|
Text
ARTIKEL KI.pdf Restricted to Repository staff only Download (1MB) |
Abstract
Cyclophosphamide is one of the chemotherapy drugs that in its use can form acrolein that triggers oxidative stress in various organs such as reproduction organ. Zinc is an important mineral for the body because it has an anti-inflammatory and antioxidant effects. This study aims to find out the histopathology of seminiferous tubules after zinc administration in mice (Mus musculus) that induced by cyclophosphamide. This study used 30 mice that were grouped into 6 groups: a group was not given zinc and cyclophosphamide (K1), only given zinc (K2), a group that was only given cyclophosphamide (K3), and 3 groups were given cyclophosphamide and zinc at doses of 25 mg (K4), 50 mg (K5), and 100 mg (K6). One Way Anova test of seminiferous tubule diameter showed significant results (p<0.05) while in One Way Anova test of tubule epithelium thickness showed insignificant results (p>0.05). Pearson Correlation Test between tubule epithelium thickness and seminiferous tubule showed strong and directly proportional correlation results. This study showed that zinc administration is considered to have an antioxidant effect which is very useful in counteracting free radicals caused by cyclophosphamide induction.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | [No. Panggil : 1710211011] [Pembimbing : . Retno Yulianti,] [Penguji : . Maria Selvester Thadeus, ] |
| Uncontrolled Keywords: | Cyclophosphamide, zinc, seminiferous tubule diameter, tubule epithelium thickness |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RB Pathology R Medicine > RG Gynecology and obstetrics R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Kedokteran > Program Studi Kedokteran (S1) |
| Depositing User: | Adinda Triany Putri |
| Date Deposited: | 20 May 2022 08:59 |
| Last Modified: | 20 May 2022 08:59 |
| URI: | http://repository.upnvj.ac.id/id/eprint/11601 |
Actions (login required)
 |
View Item |